Mechanobiology and biofluidics

- mechabiofluidics -

MECABIOFLUIDICS team addresses biophysics-related scientific questions thanks to microfluidic technologies. We focus on the interplay between permeability, mechanical properties, and biological activity of tissues and cells. Applications range from the role of mechanics in cancer to filtration, and cell sorting in the blood.

HEAD

Morgan Delarue

PHD DELEGATE

Michaël Toublanc

We address biophysics-related scientific questions thanks to microfluidic technologies. See our Research topics below.

(Bio)filtration-on-chip, or how to study microscale filtration mechanisms.

We use microfluidic models of filtration membranes to study bio-clogging.

Microvasculature on chip: deformation, permeation and immunomodulation of lymphatic and blood vessels

We study the barrier and immunomodulation functions of vascular tissues with organ-on-chip technologies.

Impact of spatial confinement on cell physiology

We use microfluidics to study the impact of confinement on the behavior of living cells.

Cells and extracellular vesicles: Microfluidics for their purification and the analysis of their nucleic acid composition

We develop microfluidic technologies for purifying cells and extracellular vesicles.

Mechanics of multicellular aggregates, and their interactions with nanoparticles

We develop an original fluidic technology for measuring the mechanical properties of cell aggregates (micropipettes on a chip), fundamental to many biological processes.

Head

Morgan
Delarue

Scientific executive

Aurélien
Bancaud

Jean
Cacheux

Anne-Marie
Gue

Pierre
Joseph

Contractor researcher

Francesca
Baldini

ITA contractor

Frank
Bardie

Dimitri
Radajewski

Zélie
Salvioli

Postdoctoral

Bénédicte
Alary

Daniel
Alcaide Martin

Jules
Edwards

PhD

Adélie
Barnetche

Silvia
Ferrer Royo

Jade
Genetelli

Amélie
Guerre

Hyojun
Kim

François
Lambeaux

Pierre
Lapeze

Moetassem Billah
Meksassi

Nicolas
Nguyen

Thomas
Quenan

Vincent
Renoust

Daniel
Silveira Estrela

Roxane
Sylvestre

Michaël
Toublanc

PhD guest

Mathieu
Ghenni

Perrine
Giunchi

Partnership guest

Kevin
Demont

Aurélie
Gomes

Julie
Jambert

Julien
Lefort

Olivier
Liot Petit

Latest publications

Texte à modifier dans l’interface d’édition: champ 'rayonnement' de la page Equipe.We collaborate with several groups working on oncology and biophysics. We lead the ERC Project UnderPressure, and participate to several European and National ANR projects. See Research projects pages for details.

We are also strongly involved in the French National Network on Microfluidics GDR Micro Nano Fluidics MNF