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Jean Cacheux

Jean Cacheux

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MECHABIOFLUIDICS : Mechanobiology and biofluidics

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Latest publications

2025

Journal articles

Jean Cacheux, Thomas Quénan, Daniel Alcaide, Jose Ordonez-Miranda, Laurent Jalabert, et al.. Porohyperelastic modeling of collagen-gel responses to periodic pressure actuation shows that embedded senescent fibroblasts induce tissue softening associated with fibrous-network reorganization. Physical Review Applied, 2025, 24 (6), pp.064015. ⟨10.1103/7c89-529p⟩. ⟨hal-05399336⟩

Aurélien Bancaud, Tadaaki Nakajima, Jun-Ichi Suehiro, Baptiste Alric, Florent Morfoisse, et al.. Intraluminal pressure triggers a rapid and persistent reinforcement of endothelial barriers. Lab on a Chip, 2025, 8, ⟨10.1039/D5LC00104H⟩. ⟨hal-05018080⟩

Other documents

Thomas Quénan, Pierre Cordelier, Yukiko Matsunaga, Aurélien Bancaud, Jean Cacheux. Poromechanics of hydrogels: towards understanding colloidal transport into tissue-on-chip. Euralimms 2025, Jun 2025, Hyères, France. ⟨hal-05457641⟩

2024

Journal articles

Daniel Alcaide, Baptiste Alric, Jean Cacheux, Shizuka Nakano, Kotaro Doi, et al.. Laminin and hyaluronan supplementation of collagen hydrogels enhances endothelial function and tight junction expression on three-dimensional cylindrical microvessel-on-a-chip. Biochemical and Biophysical Research Communications, 2024, 724 (6), pp.150234. ⟨10.1016/j.bbrc.2024.150234⟩. ⟨hal-04715111⟩

Jean Cacheux, Tadaaki Nakajima, Daniel Alcaide, Takanori Sano, Kotaro Doi, et al.. Protocol for fabricating and characterizing microvessel-on-a-chip for human umbilical vein endothelial cells. STAR Protocols, 2024, 5 (2), pp.102950. ⟨10.1016/j.xpro.2024.102950⟩. ⟨hal-04715098⟩

Other documents

Jean Cacheux, Mahla Majidian Eidgahi, Pierre Cordelier. 3D in vitro model of pancreatic cancer to study oncolytic virus infection. Microphysio 2024, Sep 2024, Cargèse, France. 2024. ⟨hal-04746663⟩

2023

Journal articles

Jean Cacheux, Aurélien Bancaud, Daniel Alcaide, Jun-Ichi Suehiro, Yoshihiro Akimoto, et al.. Endothelial tissue remodeling induced by intraluminal pressure enhances paracellular solute transport. iScience, 2023, 26 (7), pp.107141. ⟨10.1016/j.isci.2023.107141⟩. ⟨hal-04250976⟩

Jean Cacheux, Jose Ordonez-Miranda, Aurélien Bancaud, Laurent Jalabert, Daniel Alcaide, et al.. Asymmetry of tensile versus compressive elasticity and permeability contributes to the regulation of exchanges in collagen gels. Science Advances , 2023, 9 (31), ⟨10.1126/sciadv.adf9775⟩. ⟨hal-04235287⟩

Daniel Alcaide, Jean Cacheux, Aurélien Bancaud, Rieko Muramatsu, Yukiko T Matsunaga. Solute transport in the brain tissue: what are the key biophysical parameters tying in vivo and in vitro studies together?. Biomaterials Science, 2023, 10, pp.3450-3460. ⟨10.1039/D3BM00027C⟩. ⟨hal-04063141⟩

Hedele Zeng, Takanori Sano, Jean Cacheux, Aurélien Bancaud, Jun-Ichi Kawabe, et al.. Capillary Stem Cells Enhance Vascular Barrier Function Revealed by the In Vitro Microvessel Model. Nanobiomedicine, 2023, 15 (2), pp.105-111. ⟨10.11344/nano.15.105⟩. ⟨hal-04715191⟩

Alberto Martín-Asensio, Sergio Dávila, Jean Cacheux, Agnieszka Lindstaedt, Alicja Dziadosz, et al.. Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction. Advanced NanoBiomed Research, 2023, 3 (6), ⟨10.1002/anbr.202200164⟩. ⟨hal-04715157⟩

2022

Conference papers

Jean Cacheux, Aurélien Bancaud, Jose Ordonez-Miranda, Laurent Jalabert, Yukiko T Matsunaga. Collagen matrix remodeling by fibroblasts monitored by interstitial flow metrology. Microphysiological systems: from organoids to organ-on-chip, Apr 2022, Cargèse, France. ⟨hal-03821244⟩

2021

Journal articles

Inga Tijunelyte, Rémi Malbec, Bayan Chami, Jean Cacheux, Christophe Dez, et al.. micro-RNA 21 detection with a limit of 2 pM in 1 min using a size-accordable concentration module operated by electrohydrodynamic actuation. Biosensors and Bioelectronics, 2021, 178, pp.112992. ⟨10.1016/j.bios.2021.112992⟩. ⟨hal-03449104⟩

Sergio Dávila, Jean Cacheux, Isabel Rodríguez. Microvessel-on-Chip Fabrication for the In Vitro Modeling of Nanomedicine Transport. ACS Omega, 2021, 6 (39), pp.25109-25115. ⟨10.1021/acsomega.1c00735⟩. ⟨inserm-04291038⟩

2019

Journal articles

Jean Cacheux, Aurélien Bancaud, Thierry Leichle, Pierre Cordelier. Technological Challenges and Future Issues for the Detection of Circulating MicroRNAs in Patients With Cancer. Frontiers in Chemistry, 2019, 7, ⟨10.3389/fchem.2019.00815⟩. ⟨hal-02392369⟩

2018

Journal articles

Hubert Ranchon, Jean Cacheux, Benjamin Reig, Olivier Liot, Pattamon Teerapanich, et al.. Accelerated transport of particles in confined channels with high roughness amplitude. Langmuir, 2018, 34 (4), pp.1394-1399. ⟨10.1021/acs.langmuir.7b03962⟩. ⟨hal-01682628⟩

Mirko Mikolasek, Maria Dolores Manrique-Juarez, H. J. Shepherd, Karl Ridier, Sylvain Rat, et al.. Complete set of elastic moduli of a spin-crossover solid: Spin-state dependence and mechanical actuation. Journal of the American Chemical Society, 2018, 140 (28), pp.8970-8979. ⟨10.1021/jacs.8b05347⟩. ⟨hal-01961781⟩

Jean Cacheux, Marie Brut, Aurélien Bancaud, Pierre Cordelier, Thierry Leichle. Spatial Analysis of Nanofluidic-Embedded Biosensors for Wash-Free Single-Nucleotide Difference Discrimination. ACS Sensors, 2018, 3 (3), pp.606 - 611. ⟨10.1021/acssensors.7b00667⟩. ⟨hal-01762631⟩

Rémi Malbec, Jean Cacheux, Pierre Cordelier, Thierry Leichle, Pierre Joseph, et al.. Microfluidics for minute DNA sample analysis: open challenges for genetic testing of cell-free circulating DNA in blood plasma. Micro and Nano Engineering, 2018, 1, pp.25-32. ⟨10.1016/j.mne.2018.10.003⟩. ⟨hal-02338521⟩

PhD thesis, HDR

Jean Cacheux. Développement d'un système autonome de détection et de quantification des microARNs avec une plateforme nanofluidique pour la prise en charge du cancer du pancréas. Cancer. Université Paul Sabatier - Toulouse III, 2018. Français. ⟨NNT : 2018TOU30152⟩. ⟨tel-01922268v2⟩

2017

Journal articles

María Dolores Manrique-Juárez, Fabrice Mathieu, Victoria Shalabaeva, Jean Cacheux, Sylvain Rat, et al.. A Bistable Microelectromechanical System Actuated by Spin-Crossover Molecules. Angewandte Chemie International Edition, 2017, 56 (28), pp.8074-8078. ⟨10.1002/anie.201702739⟩. ⟨hal-01687804⟩

Other documents

Jean Cacheux, Marie Brut, Aurélien Bancaud, Pierre Cordelier, Thierry Leichle. Rapid Discrimination Of Single-Nucleotide Differences Through The Spatial Analysis Of A Nanofluidic-Embedded Biosensor. MicroTAS, Oct 2017, Savannah, United States. 2017. ⟨hal-01699274⟩

Jean Cacheux, Pierre Cordelier, Thierry Leichle. Towards circulating microRNA detection using fluorescence-based nanofluidic platform for the early diagnosis of pancreatic cancer. 49th Meeting of European Pancreatic Club 2017, Jun 2017, Budapest, Hungary. 17 (3), 2017, ⟨10.1016/j.pan.2017.05.048⟩. ⟨hal-01699252⟩

2016

Conference papers

Jean Cacheux, Aurélien Bancaud, Pierre Cordelier, Thierry Leichle. Fast single-nucleotide polymorphism (SNP) discrimination using a fluorescence-based nanofluidic platform. NanoBioTech, Nov 2016, Montreux, Switzerland. ⟨hal-01857479⟩