High Frequency and Fluidic Micro and nanosystems

- mh2f -


The scientific context of the team focuses on the interaction and exploitation of electromagnetic fields with complex environments.


HEAD

Katia Grenier

PHD DELEGATE

Anne Calvel

Based on two main research subjects

Electromagnetic waves impacts on living organisms

This area focuses on the potential impact of electromagnetic waves on living beings. These waves are omnipresent in everyday life (telecommunications, geolocation, home automation) as well as in the military field (radar, jamming systems, weapons, protection of infantrymen, DREP). In this context, we are developing instrumentation and exposure systems dedicated to assessing and understanding the possible effects of these waves at the cellular level.

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Dielectric characterization of materials - non-invasive analysis

Non-destructive, non-invasive analysis of complex fluids, including homogeneous, heterogeneous, inert, living, static or moving media, through the development of microwave dielectric spectroscopy techniques

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Latest publications

2023

Journal articles

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. RF sensor dedicated to the dielectric characterization of spheroids between 500 MHz and 20 GHz. International Journal of Microwave and Wireless Technologies, 2023, 1 (Special Issue 10), pp.1643 - 1648. ⟨10.1017/S1759078723000508⟩. ⟨hal-04091380⟩

Marie Mertens, Maede Chavoshi, Olivia Peytral-Rieu, Katia Grenier, Dominique Schreurs. Dielectric Spectroscopy: Revealing the True Colors of Biological Matter. IEEE Microwave Magazine, 2023, 24 (4), pp.49-62. ⟨10.1109/MMM.2022.3233510⟩. ⟨hal-04091361⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Microwave-Based Sensor for the Noninvasive and Real-Time Analysis of 3-D Biological Microtissues: Microfluidic Improvement and Sensitivity Study. IEEE Transactions on Microwave Theory and Techniques, 2023, 71 (11), pp.4996 - 5003. ⟨10.1109/TMTT.2023.3267567⟩. ⟨hal-04091375⟩

Conference papers

Anne Calvel, Alexia Caro, Olivia Peytral-Rieu, David Dubuc, Grenier Katia, et al.. Performing in vitro biological assays to evaluate the impact of electrochemotherapy treatments. IEEE MTT-S International Microwave Biomedical Conference (IMBioC 2023), Sep 2023, Louvain, Belgium. ⟨10.1109/IMBioC56839.2023.10305109⟩. ⟨hal-04281240⟩

Olivia Peytral-Rieu, Yegor Kozhemyakin, Benjamin Cerdan, Anne Calvel, Yuwei Li, et al.. Interests of Microwave Dielectric Spectroscopy for biological characterizations. URSI GASS 2023, Aug 2023, Sapporo, Japan. ⟨hal-04197176⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Optimisation et évaluation de la stabilité d'un biocapteur HyperFréquence dédié à la caractérisation diélectrique de sphéroïdes de 500MHz à 20GHz. 17èmes Journées de Caractérisations Microondes et matériaux, Apr 2023, Tours, France. ⟨hal-04007888⟩

Christine Leterrier, Claire Bonnefous, Jarkko Niemi, Lucia Rocchi, Giuditta Meloni, et al.. Welfare barriers and levers for improvement in organic and low-input outdoor pig and poultry production systems. 74. Annual meeting of the european federation of animal science (EAAP 2023), EAAP, Aug 2023, Lyon, France. pp.731. ⟨hal-04198015⟩

2022

Journal articles

Amar Tamra, Amel Zedek, Marie-Pierre Rols, David Dubuc, Katia Grenier. Single cell microwave biosensor for monitoring cellular response to electrochemotherapy. IEEE Transactions on Biomedical Engineering, 2022, 69 (11), pp.3407 - 3414. ⟨10.1109/TBME.2022.3170267⟩. ⟨hal-03713284⟩

Jonathan Munoz-Enano, Olivia Peytral-Rieu, Paris Velez, David Dubuc, Katia Grenier, et al.. Characterization of the Denaturation of Bovine Serum Albumin (BSA) Protein by Means of a Differential-Mode Microwave Microfluidic Sensor Based on Slot Resonators. IEEE Sensors Journal, 2022, 22 (14), pp.14075 - 14083. ⟨10.1109/JSEN.2022.3181542⟩. ⟨hal-03714052⟩

Conference papers

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Microwave Microfabricated Sensor Dedicated to the Dielectric Characterization of Biological Microtissues. 2022 3rd URSI Atlantic and Asia Pacific Radio Science Meeting (AT-AP-RASC), May 2022, Gran Canaria, Spain. ⟨10.23919/AT-AP-RASC54737.2022.9814189⟩. ⟨hal-03713832⟩

Ali Moscatiello, Benjamin Cerdan, Camille Gironde, Christophe Furger, David Dubuc, et al.. Dosimetry Performances of a MultiWell-Plate-Based Near-Field RF Applicator for the Investigation of EM Impact on Biological Cells. IEEE MTT-S International Microwave Symposium (IMS 2022), Jun 2022, Denver, United States. ⟨10.1109/IMS37962.2022.9865593⟩. ⟨hal-03713378⟩

Katia Grenier, David Dubuc. Evaluation of the impact of RF electromagnetic waves on cells with near-field exposure instrumentations. IEEE MTT-S International Microwave Symposium 2022, Jun 2022, Denver, United States. ⟨hal-03713432⟩

Katia Grenier, Olivia Peytral-Rieu, David Dubuc. Extension of possibilities for non-invasive analysis by microwave spectroscopy of 3D biological models. IEEE International Microwave Biomedical Conference 2022, May 2022, Suzhou, China. ⟨hal-03713345⟩

Olivia Peytral-Rieu, D Dubuc, K Grenier. Dispositif RF dédié à la détermination des propriétés diélectriques de sphéroïdes entre 500 MHz et 20 GHz. XXIIèmes Journées Nationales Microondes, Jun 2022, Limoges, France. ⟨hal-03713834⟩

A Moscatiello, B Cerdan, David Dubuc, Katia Grenier. Caractérisation dosimétrique d'un applicateur RF en champ proche adapté aux plaques à puits de tests biologiques pour étudier l'impact des ondes EM sur cellules. Journées Nationales Microondes, Jun 2022, Limoges, France. ⟨hal-03714578⟩

Yegor Kozhemyakin, Sophie Réhault-Godbert, David Dubuc, Katia Grenier. Millifluidic Sensor Designed to Perform the Microwave Dielectric Spectroscopy of Biological Liquids. 2022 European Microwave Conference, Sep 2022, Milan, Italy. pp.412-415, ⟨10.23919/EuMC54642.2022.9924355⟩. ⟨hal-03805540⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Real-time analysis of electroporation phenomenon of individual cells. Electroporation-Based Technologies and Treatments, Nov 2022, Ljubljana, Slovenia. ⟨hal-04281266⟩

Anne Collin, Giuditta Meloni, Claire Bonnefous, Martina Re, Laura van Vooren, et al.. The PPILOW project: Innovations improving welfare in low input and organic pig and poultry farms. 73. Annual meeting of the european federation of animal science (EAAP), EAAP, Sep 2022, Porto, Portugal. pp.350. ⟨hal-04128847⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Non-invasive real time analysis of electroporation phenomenon of individual cells. World Congress on Electroporation and Pulsed Electric Fields, Oct 2022, Copenhagen, Denmark. ⟨hal-04281274⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Analyse en temps réel du phénomène d'électroporation de cellules individuelles. GDR HappyBio, Nov 2022, Albi, France. ⟨hal-04281279⟩

2021

Book sections

Hélène Martin-Yken, Christophe Furger. Cell- and Tissue-Containing Biosensors. Elsevier. Encyclopedia of Sensors and Biosensors Reference Module in Biomedical Sciences, Elsevier, Chapter 29, 2021, Encyclopedia of Sensors and Biosensors, ⟨10.1016/B978-0-12-822548-6.00062-5⟩. ⟨hal-03330028⟩

Conference papers

Olivia Peytral-Rieu, Katia Grenier, David Dubuc. Microwave Sensor Dedicated to the Determination of the Dielectric Properties of 3D Biological Models from 500MHz to 20GHz. IEEE MTT-S International Microwave Symposium (IMS 2021), Jun 2021, Atlanta, United States. ⟨10.1109/IMS19712.2021.9574794⟩. ⟨hal-03354050v2⟩

Cristina Micheloni, An Jamart, Martina Re, Laura van Vooren, Jarkko Niemi, et al.. The multi-actor PPILOW European project: a participative approach to co-build innovations for welfare improvement in organic pig and poultry farms. Organic World Congress 2021, IFOAM, Sep 2021, Rennes, France. pp.42-43. ⟨hal-03629772⟩

Katia Grenier, W. Chen, David Dubuc. Non-invasive real time monitoring of cellular modifications with microwave dielectric spectroscopy at the single cell level. 2021 XXXIVth General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS), Aug 2021, Rome, Italy. pp.1-3, ⟨10.23919/URSIGASS51995.2021.9560506⟩. ⟨hal-03407670⟩

Lucia Rocchi, Anne Collin, Giuditta Meloni, Claire Bonnefous, Martina Re, et al.. PPILOW: innovations for improving animal welfare and human well-being in low-input outdoor and organic poultry and pig production systems. One Welfare World Conference, 2021, One Welfare CIC, Sep 2021, Online meeting, Spain. pp.46. ⟨hal-03632430⟩

Amar Tamra, Katia Grenier, Marie-Pierre Rols, David Dubuc. Microwave dielectric spectroscopy of individual electroporated cells. 2021 XXXIVth General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS), Aug 2021, Rome, Italy. pp.1-4, ⟨10.23919/URSIGASS51995.2021.9560287⟩. ⟨hal-03407650⟩

Autres documents

Katia Grenier, Dominique Schreurs. The IEEE International Microwave Biomedical Conference 2020. 2021, pp.77-79; 89. ⟨10.1109/MMM.2021.3096005⟩. ⟨hal-03436961⟩

2020

Journal articles

Guillaume Poiroux, David Dubuc, Mohsen Hosseini, François Artis, Amar Tamra, et al.. Label-free detection of mitochondrial activity with Microwave Dielectric Spectroscopy Research Article. International Journal of Biotechnology and Bioengineering, 2020, 6 (5). ⟨hal-03027924⟩

Conference papers

A Tamra, David Dubuc, M P Rols, Katia Grenier. Caractérisation micro-ondes de cellules biologiques soumises à différents stimuli chimiques. 16èmes Journées de Caractérisation Microondes et Matériaux, Nov 2020, Toulouse, France. ⟨hal-03028001⟩

Sylvain Auge, Amar Tamra, L. Rigal, V. Lobjois, B. Ducommun, et al.. Experimental Dosimetry Study of a Miniature RF Applicator Dedicated to the Evaluation of Severe RF Exposure Impact on a 3D Biological Model. 2020 IEEE/MTT-S International Microwave Symposium (IMS), Aug 2020, Los Angeles, United States. pp.508-511, ⟨10.1109/IMS30576.2020.9223806⟩. ⟨hal-03027950⟩

Maréva Calvet-Chautard, Patricio Jaque Gonzalez, Thierry Véronèse, David Dubuc, Katia Grenier. Microwave-Based Sensor Dedicated to the Characterization of Meat Freshness. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtual), France. pp.1-4, ⟨10.1109/IMBIoC47321.2020.9385050⟩. ⟨hal-03253198⟩

Jelena Kolosnjaj-Tabi, Geraldine Alberola, Sylvain Augé, Amar Tamra, David Dubuc, et al.. Evaluation of Cell Membrane Effects After 3D Multicellular Spheroids RF Exposure. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtuel), France. pp.1-3, ⟨10.1109/IMBIoC47321.2020.9385011⟩. ⟨hal-03253240⟩

Katia Grenier, Genevieve Pratviel, Hugo Mazur, David Dubuc. Detection of a Macromolecule Denaturation With Microwave Dielectric Spectroscopy based on Hydration Modifications. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtual), France. ⟨10.1109/IMBIoC47321.2020.9385022⟩. ⟨hal-03253166⟩

2019

Journal articles

Paris Velez, Jonathan Munoz-Enano, Katia Grenier, Javier Mata-Contreras, David Dubuc, et al.. Split Ring Resonator-Based Microwave Fluidic Sensors for Electrolyte Concentration Measurements. IEEE Sensors Journal, 2019, 19 (7), pp.2562-2569. ⟨10.1109/JSEN.2018.2890089⟩. ⟨hal-02401048⟩

Amar Tamra, David Dubuc, Marie-Pierre Rols, Katia Grenier. Evaluation of a Microwave Biosensor for On-Chip Electroporation and Efficient Molecular Delivery Into Mammalian Cells. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 2019, 3 (3), pp.224-231. ⟨10.1109/JERM.2019.2898318⟩. ⟨hal-02400977⟩

Conference papers

J Muñoz-Enano, P Vélez, M. Gil, J. Mata-Contreras, Katia Grenier, et al.. Microstrip Lines Loaded with Metamaterial-Inspired Resonators for Microwave Sensors/Comparators with Optimized Sensitivity. 49th European Microwave Conference (EuMC 2019), Oct 2019, Paris, France. pp.754-757, ⟨10.23919/EuMC.2019.8910702⟩. ⟨hal-02401018⟩

Amar Tamra, M.-P. Rols, David Dubuc, Katia Grenier. Impact of a chemical stimulus on two different cell lines through microwave dielectric spectroscopy at the single cell level. IEEE MTT-S International Microwave Biomedical Conference (IMBioC 2019), May 2019, Nanjing, China. pp.1-4, ⟨10.1109/IMBIOC.2019.8777745⟩. ⟨hal-02401032⟩

A Tamra, David Dubuc, M P Rols, Katia Grenier. Microwave dielectric spectroscopy as an analytic technique of electroporated cells. 3rd World Congress on Electroporation & Pulsed Electric Fields in Biology, Medicine, Food and Environmental Technologies, Sep 2019, Toulouse, France. ⟨hal-03027987⟩

David Dubuc, Thomas Chretiennot, Katia Grenier. Microwave based resonant biosensors for multiple molecular concentrations quantification. 2019 International Conference on Electromagnetics in Advanced Applications (ICEAA), Sep 2019, Granada, Spain. ⟨10.1109/ICEAA.2019.8879301⟩. ⟨hal-02400953⟩

Patricio Felipe Jaque Gonzalez, David Dubuc, Katia Grenier, T. Veronese. Millifluidic Sensor Dedicated to the Microwave Dielectric Spectroscopy of Liquids. 2019 49th European Microwave Conference (EuMC), Oct 2019, Paris, France. pp.204-207, ⟨10.23919/EuMC.2019.8910952⟩. ⟨hal-02400996⟩

Autres documents

James C. Hwang, Olivia Peytral-Rieu, Maurice Philippson. A translation of Maurice Philippson's "Principles of the Electrical Resistance of Living Tissue". 2019, ⟨10.48550/arXiv.2105.06428⟩. ⟨hal-03951612⟩

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