Micro et nanosystèmes HyperFréquences Fluidiques

- mh2f -


Le contexte scientifique de l'équipe vise à comprendre et exploiter l’interaction des champs électromagnétiques avec des milieux complexes pour de l'analyse non destructive et non-invasive et l'évaluation de l'impact des ondes électromagnétiques sur le vivant.


RESPONSABLE

Katia Grenier

Les activités de recherche sont structurées selon 2 orientations.

Caractérisation diélectrique de la matière - Analyse non-invasive

L’analyse non destructive et non invasive des fluides complexes incluant les milieux homogènes, hétérogènes, inertes, vivants, statiques ou en mouvement, par le développement de la technique de spectroscopie diélectrique micro-onde

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Effets des ondes électromagnétiques sur le vivant

Cette orientation vise l'étude de l’impact potentiel des ondes électromagnétiques sur le vivant. Ces ondes sont en effet omniprésentes dans la vie courante (télécommunications, géolocalisation, domotique) ainsi que dans le domaine militaire (radars, systèmes de brouillage, armes, protection des fantassins, DREP). Dans ce cadre, nous développons des instrumentations et systèmes d'exposition dédiés à l'évaluation et la compréhension des effets possibles de ces ondes à l’échelle cellulaire.

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Dernières Publications

2024

Articles dans une revue

Anne Calvel, Olivia Peytral-Rieu, Marie-Pierre Rols, David Dubuc, Katia Grenier. Extension to In Situ Single-Cell Electroporation of a Microwave Biosensor. IEEE Microwave and Wireless Technology Letters, 2024, 34 (6), pp.849 - 852. ⟨10.1109/lmwt.2024.3391213⟩. ⟨hal-04651131⟩

Anne Calvel, Alexia de Caro, Olivia Peytral-Rieu, Camille Gironde, Christophe Furger, et al.. Analysis of In Vitro Cell Viability Approaches to Provide Early Efficacy Prediction of Electrochemotherapy Treatments. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, In press, pp.1-9. ⟨10.1109/JERM.2024.3379012⟩. ⟨hal-04650849v2⟩

Jérôme Devoy, Souhail Al-Abed, Benjamin Cerdan, Wan-Seob Cho, David Dubuc, et al.. Analysis of carbon nanotube levels in organic matter: an inter-laboratory comparison to determine best practice. Nanotoxicology, 2024, 18 (3), 15p. ⟨10.1080/17435390.2024.2331683⟩. ⟨hal-04538836⟩

Communications dans un congrès

Anne Calvel, Olivia Peytral-Rieu, David Dubuc, Katia Grenier, Marie-Pierre Rols. Validation of in situ electroporation performed within a single cell microwave biosensor. 5th World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Sep 2024, Rome, Italy. ⟨hal-04671854⟩

Olivia Peytral-Rieu, Yuwei Li, David Dubuc, Katia Grenier. Suivi en temps réel de l'effet de la TSA sur des sphéroïdes par spectroscopie diélectriques microondes entre 500MHz et 20GHz. XXIIIème Journées Nationales Microondes, Jun 2024, Antibes - Juan les Pins, France. ⟨hal-04773798⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Miniature microwave sensor suitable for real-time dielectric analysis of multicellular spheroids. NanoBioTech - Montreux Conference, Nov 2024, Montreux (Switzerland), Switzerland. ⟨hal-04774221⟩

Yuwei Li, Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Modeling a 4-port Microwave-Based Biosensor for 3D Models Mapping. European Microwave Conference 2024, Sep 2024, Paris, France. ⟨hal-04772192⟩

A Calvel, Olivia Peytral-Rieu, Marie-Pierre Rols, David Dubuc, Katia Grenier. Extension d'un biocapteur hyperfréquences à l'électroporation in situ de cellules individuelles. XXIIIèmes Journées Nationales Microondes, Jun 2024, Antibes Juan-Les-Pins, France. ⟨hal-04651136⟩

Sophie Réhault-Godbert, Katia Grenier. In ovo sexing tools. PPILOW Final conference, Anne Collin; Anthonie Vermue, Jun 2024, Tervuren, Belgium. ⟨hal-04627851⟩

2023

Articles dans une revue

Marie Mertens, Maede Chavoshi, Olivia Peytral-Rieu, Katia Grenier, Dominique Schreurs. Dielectric Spectroscopy: Revealing the True Colors of Biological Matter. IEEE Microwave Magazine, 2023, 24 (4), pp.49-62. ⟨10.1109/MMM.2022.3233510⟩. ⟨hal-04091361⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. RF sensor dedicated to the dielectric characterization of spheroids between 500 MHz and 20 GHz. International Journal of Microwave and Wireless Technologies, 2023, 1 (Special Issue 10), pp.1643 - 1648. ⟨10.1017/S1759078723000508⟩. ⟨hal-04091380⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Microwave-Based Sensor for the Noninvasive and Real-Time Analysis of 3-D Biological Microtissues: Microfluidic Improvement and Sensitivity Study. IEEE Transactions on Microwave Theory and Techniques, 2023, 71 (11), pp.4996 - 5003. ⟨10.1109/TMTT.2023.3267567⟩. ⟨hal-04091375⟩

Communications dans un congrès

Cerdan Benjamin, Flahaut Emmanuel, Dubuc David, Katia Grenier. Comparison of Two Thermal Probe Technologies for the Dosimetric Investigations of RF Exposure Systems. 2023 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Sep 2023, Leuven, Belgium. pp.1-3, ⟨10.1109/IMBioC56839.2023.10305111⟩. ⟨hal-04772130⟩

Christine Leterrier, Claire Bonnefous, Jarkko Niemi, Lucia Rocchi, Giuditta Meloni, et al.. Welfare barriers and levers for improvement in organic and low-input outdoor pig and poultry production systems. 74. Annual meeting of the european federation of animal science (EAAP 2023), EAAP, Aug 2023, Lyon, France. pp.731. ⟨hal-04198015⟩

Anne Calvel, Alexia Caro, Olivia Peytral-Rieu, David Dubuc, Grenier Katia, et al.. Performing in vitro biological assays to evaluate the impact of electrochemotherapy treatments. IEEE MTT-S International Microwave Biomedical Conference (IMBioC 2023), Sep 2023, Louvain, Belgium. ⟨10.1109/IMBioC56839.2023.10305109⟩. ⟨hal-04281240⟩

Katia Grenier, Olivia Peytral-Rieu, Yuwei Li, Anne Calvel, Yegor Kozhemyakin, et al.. Non invasive microwave dielectric spectroscopy for biological characterization and healthcare applications : Importance of a differential approach. IEEE CAMA 2023, Nov 2023, Genoa Italy, Italy. ⟨hal-04490995⟩

Olivia Peytral-Rieu, Yegor Kozhemyakin, Benjamin Cerdan, Anne Calvel, Yuwei Li, et al.. Interests of Microwave Dielectric Spectroscopy for biological characterizations. URSI GASS 2023, Aug 2023, Sapporo, Japan. ⟨hal-04197176⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Optimisation et évaluation de la stabilité d'un biocapteur HyperFréquence dédié à la caractérisation diélectrique de sphéroïdes de 500MHz à 20GHz. 17èmes Journées de Caractérisations Microondes et matériaux, Apr 2023, Tours, France. ⟨hal-04007888⟩

Autres documents

Aube Darves-Bornoz, Emmanuel Barbeau, Anne Calvel, Marie Denuelle, Kim Guines, et al.. Going beyond the empirical and historical parameters of intracranial electrical brain stimulations to improve the yield of stereo-electroencephalography. European Congress of Clinical Neurophysiology 2023, May 2023, Marseille, France. Clinical Neurophysiology, 150, pp.e174-e175, 2023, ⟨10.1016/j.clinph.2023.03.304⟩. ⟨hal-04768289⟩

2022

Articles dans une revue

Jonathan Munoz-Enano, Olivia Peytral-Rieu, Paris Velez, David Dubuc, Katia Grenier, et al.. Characterization of the Denaturation of Bovine Serum Albumin (BSA) Protein by Means of a Differential-Mode Microwave Microfluidic Sensor Based on Slot Resonators. IEEE Sensors Journal, 2022, 22 (14), pp.14075 - 14083. ⟨10.1109/JSEN.2022.3181542⟩. ⟨hal-03714052⟩

Amar Tamra, Amel Zedek, Marie-Pierre Rols, David Dubuc, Katia Grenier. Single cell microwave biosensor for monitoring cellular response to electrochemotherapy. IEEE Transactions on Biomedical Engineering, 2022, 69 (11), pp.3407 - 3414. ⟨10.1109/TBME.2022.3170267⟩. ⟨hal-03713284⟩

Communications dans un congrès

Yegor Kozhemyakin, Sophie Réhault-Godbert, David Dubuc, Katia Grenier. Millifluidic Sensor Designed to Perform the Microwave Dielectric Spectroscopy of Biological Liquids. 2022 European Microwave Conference, Sep 2022, Milan, Italy. pp.412-415, ⟨10.23919/EuMC54642.2022.9924355⟩. ⟨hal-03805540⟩

Olivia Peytral-Rieu, David Dubuc, Katia Grenier. Microwave Microfabricated Sensor Dedicated to the Dielectric Characterization of Biological Microtissues. 2022 3rd URSI Atlantic and Asia Pacific Radio Science Meeting (AT-AP-RASC), May 2022, Gran Canaria, Spain. ⟨10.23919/AT-AP-RASC54737.2022.9814189⟩. ⟨hal-03713832⟩

Ali Moscatiello, Benjamin Cerdan, Camille Gironde, Christophe Furger, David Dubuc, et al.. Dosimetry Performances of a MultiWell-Plate-Based Near-Field RF Applicator for the Investigation of EM Impact on Biological Cells. IEEE MTT-S International Microwave Symposium (IMS 2022), Jun 2022, Denver, United States. ⟨10.1109/IMS37962.2022.9865593⟩. ⟨hal-03713378⟩

Katia Grenier, David Dubuc. Evaluation of the impact of RF electromagnetic waves on cells with near-field exposure instrumentations. IEEE MTT-S International Microwave Symposium 2022, Jun 2022, Denver, United States. ⟨hal-03713432⟩

Katia Grenier, Olivia Peytral-Rieu, David Dubuc. Extension of possibilities for non-invasive analysis by microwave spectroscopy of 3D biological models. IEEE International Microwave Biomedical Conference 2022, May 2022, Suzhou, China. ⟨hal-03713345⟩

Olivia Peytral-Rieu, D Dubuc, K Grenier. Dispositif RF dédié à la détermination des propriétés diélectriques de sphéroïdes entre 500 MHz et 20 GHz. XXIIèmes Journées Nationales Microondes, Jun 2022, Limoges, France. ⟨hal-03713834⟩

A Moscatiello, B Cerdan, David Dubuc, Katia Grenier. Caractérisation dosimétrique d'un applicateur RF en champ proche adapté aux plaques à puits de tests biologiques pour étudier l'impact des ondes EM sur cellules. Journées Nationales Microondes, Jun 2022, Limoges, France. ⟨hal-03714578⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Real-time analysis of electroporation phenomenon of individual cells. Electroporation-Based Technologies and Treatments, Nov 2022, Ljubljana, Slovenia. ⟨hal-04281266⟩

Anne Collin, Giuditta Meloni, Claire Bonnefous, Martina Re, Laura van Vooren, et al.. The PPILOW project: Innovations improving welfare in low input and organic pig and poultry farms. 73. Annual meeting of the european federation of animal science (EAAP), EAAP, Sep 2022, Porto, Portugal. pp.350. ⟨hal-04128847⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Non-invasive real time analysis of electroporation phenomenon of individual cells. World Congress on Electroporation and Pulsed Electric Fields, Oct 2022, Copenhagen, Denmark. ⟨hal-04281274⟩

Anne Calvel, Katia Grenier, David Dubuc, Marie-Pierre Rols. Analyse en temps réel du phénomène d'électroporation de cellules individuelles. GDR HappyBio, Nov 2022, Albi, France. ⟨hal-04281279⟩

2021

Chapitres d’ouvrages

Hélène Martin-Yken, Christophe Furger. Cell- and Tissue-Containing Biosensors. Elsevier. Encyclopedia of Sensors and Biosensors Reference Module in Biomedical Sciences, Elsevier, Chapter 29, 2021, Encyclopedia of Sensors and Biosensors, ⟨10.1016/B978-0-12-822548-6.00062-5⟩. ⟨hal-03330028⟩

Communications dans un congrès

Katia Grenier, W. Chen, David Dubuc. Non-invasive real time monitoring of cellular modifications with microwave dielectric spectroscopy at the single cell level. 2021 XXXIVth General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS), Aug 2021, Rome, Italy. pp.1-3, ⟨10.23919/URSIGASS51995.2021.9560506⟩. ⟨hal-03407670⟩

Amar Tamra, Katia Grenier, Marie-Pierre Rols, David Dubuc. Microwave dielectric spectroscopy of individual electroporated cells. 2021 XXXIVth General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS), Aug 2021, Rome, Italy. pp.1-4, ⟨10.23919/URSIGASS51995.2021.9560287⟩. ⟨hal-03407650⟩

Lucia Rocchi, Anne Collin, Giuditta Meloni, Claire Bonnefous, Martina Re, et al.. PPILOW: innovations for improving animal welfare and human well-being in low-input outdoor and organic poultry and pig production systems. One Welfare World Conference, 2021, One Welfare CIC, Sep 2021, Online meeting, Spain. pp.46. ⟨hal-03632430⟩

Cristina Micheloni, An Jamart, Martina Re, Laura van Vooren, Jarkko Niemi, et al.. The multi-actor PPILOW European project: a participative approach to co-build innovations for welfare improvement in organic pig and poultry farms. Organic World Congress 2021, IFOAM, Sep 2021, Rennes, France. pp.42-43. ⟨hal-03629772⟩

Olivia Peytral-Rieu, Katia Grenier, David Dubuc. Microwave Sensor Dedicated to the Determination of the Dielectric Properties of 3D Biological Models from 500MHz to 20GHz. IEEE MTT-S International Microwave Symposium (IMS 2021), Jun 2021, Atlanta, United States. ⟨10.1109/IMS19712.2021.9574794⟩. ⟨hal-03354050v2⟩

Autres documents

Katia Grenier, Dominique Schreurs. The IEEE International Microwave Biomedical Conference 2020. 2021, pp.77-79; 89. ⟨10.1109/MMM.2021.3096005⟩. ⟨hal-03436961⟩

2020

Articles dans une revue

Guillaume Poiroux, David Dubuc, Mohsen Hosseini, François Artis, Amar Tamra, et al.. Label-free detection of mitochondrial activity with Microwave Dielectric Spectroscopy. International Journal of Biotechnology and Bioengineering, 2020, 6 (5). ⟨hal-03027924⟩

Communications dans un congrès

Katia Grenier, Genevieve Pratviel, Hugo Mazur, David Dubuc. Detection of a Macromolecule Denaturation With Microwave Dielectric Spectroscopy based on Hydration Modifications. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtual), France. ⟨10.1109/IMBIoC47321.2020.9385022⟩. ⟨hal-03253166⟩

A Tamra, David Dubuc, Marie-Pierre Rols, Katia Grenier. Caractérisation micro-ondes de cellules biologiques soumises à différents stimuli chimiques. 16èmes Journées de Caractérisation Microondes et Matériaux, Nov 2020, Toulouse, France. ⟨hal-03028001⟩

Maréva Calvet-Chautard, Patricio Jaque Gonzalez, Thierry Véronèse, David Dubuc, Katia Grenier. Microwave-Based Sensor Dedicated to the Characterization of Meat Freshness. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtual), France. pp.1-4, ⟨10.1109/IMBIoC47321.2020.9385050⟩. ⟨hal-03253198⟩

Jelena Kolosnjaj-Tabi, Geraldine Alberola, Sylvain Augé, Amar Tamra, David Dubuc, et al.. Evaluation of Cell Membrane Effects After 3D Multicellular Spheroids RF Exposure. 2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Dec 2020, Toulouse (virtuel), France. pp.1-3, ⟨10.1109/IMBIoC47321.2020.9385011⟩. ⟨hal-03253240⟩

Sylvain Auge, Amar Tamra, L. Rigal, V. Lobjois, B. Ducommun, et al.. Experimental Dosimetry Study of a Miniature RF Applicator Dedicated to the Evaluation of Severe RF Exposure Impact on a 3D Biological Model. 2020 IEEE/MTT-S International Microwave Symposium (IMS), Aug 2020, Los Angeles, United States. pp.508-511, ⟨10.1109/IMS30576.2020.9223806⟩. ⟨hal-03027950⟩

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