2024

Journal articles

Chanaëlle Febrissy, Marine Adlanmerini, Christel Péqueux, Frederic Boudou, Melissa Buscato, et al.. Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth. Theranostics, 2024, Theranostics, 14 (1), pp.249-264. ⟨10.7150/thno.87306⟩. ⟨hal-04384793⟩

Marion Régnier, Arnaud Polizzi, Tiffany Fougeray, Anne Fougerat, Prunelle Perrier, et al.. p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD. BioRxiv, 2024, ⟨10.1101/2024.01.09.574858⟩. ⟨hal-04442467⟩

2022

Journal articles

Carline Chaves-Almagro, Johanna Auriau, Alizée Dortignac, Pascal Clerc, Hubert Lulka, et al.. Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development. International Journal of Molecular Sciences, 2022, 23 (18), pp.10600. ⟨10.3390/ijms231810600⟩. ⟨hal-03782763⟩

Carline Chaves-Almagro, Johanna Auriau, Alizée Dortignac, Pascal Clerc, Hubert Lulka, et al.. Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development. International Journal of Molecular Sciences, 2022, 23 (18), pp.10600. ⟨10.3390/ijms231810600⟩. ⟨hal-04273227⟩

Preprints, Working Papers, ...

M. Di-Luoffo, C. Schmitter, E.C. Barrere, N. Therville, Morgan Delarue, et al.. The biomechanical context influences the PI3K output signaling in breast and pancreatic cancer cells. 2022. ⟨hal-03808261⟩

2021

Journal articles

Benoit Thibault, Fernanda Ramos‐delgado, Elvire Pons‐tostivint, Nicole Therville, Celia Cintas, et al.. Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component. EMBO Molecular Medicine, 2021, 13 (7), pp.e13502. ⟨10.15252/emmm.202013502⟩. ⟨hal-03625379⟩

M. Di-Luoffo, Zacchari Ben-Meriem, P. Lefebvre, Morgan Delarue, Julie Guillermet-Guibert. PI3K functions as a hub in mechanotransduction. Trends in Biochemical Sciences, 2021, 46 (11), pp.878-888. ⟨10.1016/j.tibs.2021.05.005⟩. ⟨hal-03252135⟩

Preprints, Working Papers, ...

C Cintas, T Douche, Z Dantes, E Mouton-Barbosa, Mp Bousquet, et al.. Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance: Mapping PI3K inhibitor-dependent phosphoproteome. 2021. ⟨hal-03223423⟩

2020

Journal articles

Davit Hakobyan, Chantal Medina, Nathalie Dusserre, Marie-Laure Stachowicz, Charles Handschin, et al.. Laser-assisted 3D bioprinting of exocrine pancreas spheroid models for cancer initiation study. Biofabrication, 2020, 12 (3), pp.035001. ⟨10.1088/1758-5090/ab7cb8⟩. ⟨inserm-02870465⟩

Ilaria Francesca Rizzuti, Pietro Mascheroni, Silvia Arcucci, Zacchari Ben-Mériem, Audrey Prunet, et al.. Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents. Physical Review Letters, 2020, 125 (12), pp.128103. ⟨10.1103/PhysRevLett.125.128103⟩. ⟨hal-02943906⟩

2019

Journal articles

Nicole Therville, Silvia Arcucci, Aurélie Vertut, Fernanda Ramos-Delgado, Dina Ferreira da Mota, et al.. Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging. Theranostics, 2019, 9, ⟨10.7150/thno.34066⟩. ⟨hal-02500120⟩

Audrey Zamora, Melinda Alves, Charlotte Chollet, Nicole Therville, Tiffany Fougeray, et al.. Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis. Cell Death and Disease, 2019, 10 (12), 12 p. ⟨10.1038/s41419-019-2181-1⟩. ⟨hal-02622895⟩

2018

Journal articles

Florent Morfoisse, Florence Tatin, Benoit Chaput, Nicole Therville, Charlotte Vaysse, et al.. Lymphatic Vasculature Requires Estrogen Receptor- Signaling to Protect From Lymphedema. Arteriosclerosis, Thrombosis, and Vascular Biology, 2018, 38 (6), pp.1346-1357. ⟨10.1161/ATVBAHA.118.310997⟩. ⟨hal-01863214⟩

Celia Cintas, Thibaut Douche, Nicole Therville, Silvia Arcucci, Fernanda Ramos-Delgado, et al.. Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics. Cancers, 2018, 10 (6), pp.174. ⟨10.3390/cancers10060174⟩. ⟨hal-02500132⟩

2017

Journal articles

Nicolas Chuvin, David Vincent, Roxane Pommier, Lindsay B Alcaraz, Johann Gout, et al.. Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRAS G12D -driven Pancreatic Tumorigenesis. Cellular and Molecular Gastroenterology and Hepatology, 2017, 4 (2), pp.263-282. ⟨10.1016/j.jcmgh.2017.05.005⟩. ⟨hal-02284709⟩

2016

Journal articles

F. Morfoisse, F. Tatin, F. Hantelys, A. Adoue, A.-C. Helfer, et al.. Nucleolin Promotes Heat Shock-Associated Translation of VEGF-D to Promote Tumor Lymphangiogenesis. Cancer Research, 2016, 76 (15), pp.4394-4405. ⟨10.1158/0008-5472.CAN-15-3140⟩. ⟨hal-02294493⟩

2015

Journal articles

Laetitia Ligat, Nathalie Saint-Laurent, Aïcha El-Mrani, Véronique Gigoux, Talal Al Saati, et al.. Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models. British Journal of Cancer, 2015, 113 (11), pp.1590 - 1598. ⟨10.1038/bjc.2015.370⟩. ⟨hal-01926958⟩

Julie Guillermet-Guibert, Lee B. Smith, Guillaume Halet, Maria A. Whitehead, Wayne Pearce, et al.. Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells. PLoS Genetics, 2015, 11 (7), pp.e1005304. ⟨10.1371/journal.pgen.1005304⟩. ⟨hal-01175530⟩

2014

Journal articles

Florent Morfoisse, Anna Kuchnio, Clément Frainay, Anne Gomez-Brouchet, Marie-Bernadette Delisle, et al.. Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism. Cell Reports, 2014, 6 (1), pp.155-167. ⟨10.1016/j.celrep.2013.12.011⟩. ⟨hal-02631811⟩