The international autumn school on Constraint Programming, Combinatorial Optimization and Machine Learning is a joint autumn school of the Association for Constraint Programming (ACP) and 4 working groups of the CNRS research networks on Artificial Intelligence (GDR IA) and Operations Research (GDR RO). These working groups are CAVIAR (Constraints and Learning), RAP (Representation and Algorithms in Practice), ROCT (Operations Research and Constraints), GT2L (Transportation and Logistics). The purpose of the school is, first, to cover the Basics of Constraint programming, Discrete Optimization and Machine learning and, second, to present advanced combinations of at least two approaches to attack complex problems. Applications in scheduling and vehicle routing will be addressed. Training sessions and software tutorials will be organized.