117documents trouvés
Contact force control of piezoresistive cantilevers with in-plane nanotips for femtoliter droplet deposition
D.SAYA, T.LEICHLE, J.B.POURCIEL, F.MATHIEU, C.BERGAUD , L.NICU
2I, NBS
Manifestation avec acte : 33rd International Conference on Micro and Nano Engineering (MNE2007), Copenhague (Danemark), 23-26 Septembre 2007, 2p. , N° 07440
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Abstract
For the purpose of biochip miniaturization, we developed a liquid spotter-based on silicon microcantilevers incorporating in-plane nanotips as a MEMS nanopatterning tool. We present new fabricated cantilevers with added piezoresistors for the contact force control during deposition. Matrices of droplets of 1 ¼m in diameter were achieved with a 10 ¼m interspot distance with high uniformity and high reproducibility by the nanotip cantilever with piezoresistive force controller.
Mots-Clés / Keywords
Piezoresistive cantilever; Silicon nanotip; Femtoliter droplet; Biochips;
Fabrication of oligonucleotide chips using parallel cantilever-based electrochemical deposition in picoliter volumes
E.DESCAMPS, T.LEICHLE, B.CORSO, S.LAURENT, P.MAILLEY, L.NICU, T.LIVACHE, C.BERGAUD
CEA Grenoble, NANO
Revue Scientifique : Advanced Materials, Vol.19, N°14, pp.1816-1821, Juillet 2007 , N° 06725
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110660Using dried rhodamine B fluorescence for temperature characterization of sub-micron scale devices
P.LOW, N.TAKAMA, B.J.KIM, C.BERGAUD
NANO, CNRS-IIS, University of Tokyo
Manifestation avec acte : The 14th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers'07 & Eurosensors), Lyon (France), 10-14 Juin 2007, 4p. , N° 07386
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110900Direct patterning of molecularly-imprinted microdot arrays for sensors and biochips
F.VANDEVELDE, T.LEICHLE, C.AYELA, C.BERGAUD, L.NICU, K.HAUPT
Université Compiègne, NANO
Revue Scientifique : Langmuir, Vol.23, N°12, pp.6490-6493, Mars 2007 , N° 07135
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Abstract
We have used fountain pen microlithography to deposit arrays of molecularly imprinted polymer microdots on flat substrates. We visualize analyte binding to the dots by fluorescence microscopy with the aid of fluorescein as a model analyte. Elution and readsorption of the analyte to the MIP dots were possible if the porosity of the dots was improved by a sacrificial polymeric porogen. The imprinting effect was confirmed by using compounds structurally related to fluorescein. In addition, we show with another MIP specific to 2,4-D that, apart from the direct measurement of the binding of fluorescent compounds, a competitive immunoassay-type format can also be used to transduce the binding. We believe that this technique has a strong potential for the fabrication of biomimetic microchips and other types of integrated biosensors.
Parallel detection of Si-based microcantilevers resonant frequencies using piezoresistive signals downmixing scheme
F.MATHIEU, D.SAYA, C.BERGAUD, L.NICU
2I, NANO
Revue Scientifique : IEEE Sensors Journal, Vol.7, N°2, pp.172-178, Février 2007 , N° 06203
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109200Collective fabrication of in-plane silicon nanotip for parallel femtoliter droplet deposition
D.SAYA, T.LEICHLE, J.B.POURCIEL, C.BERGAUD, L.NICU
NANO, 2I
Revue Scientifique : Journal of Micromechanics and Microengineering, Vol.17, N°1, pp.N1-N5, Janvier 2007 , N° 07137
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109603Micro-array deposition of nano-bead hexagonal crystals using silicon cantilevers
A.VALSESIA, P.COLPO, L.M.LACROIX, F.BRETAGNOL, T.MEZIANI, F.ROSSI, T.LEICHLE, L.NICU, C.BERGAUD
Ispra, NANO
Revue Scientifique : Small, Vol.2, N°12, pp.1444-1447, 2006 , N° 06232
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109641MEMS-based picoliter electrochemical cell array for the fabrication of oligonucleotide chip
T.LEICHLE, E.DESCAMPS, B.CORSO, S.LAURENT, P.MAILLEY, T.LIVACHE, J.B.POURCIEL, C.BERGAUD, L.NICU
NANO, CEA Grenoble, 2I
Manifestation avec acte : 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS'2006), Tokyo (Japon), 5-9 Novembre 2006, pp.774-776 , N° 06415
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108340Spot-in-spot hybridization of oligonucleotides addressed on a glass slide by a microcantilever based depositing device
N.BERTHET, T.LEICHLE, E.TREVISIOL, J.B.POURCIEL, D.SAYA, C.BERGAUD, L.NICU, J.M.FRANCOIS
INSAT-DGBA, 2I, NANO
Manifestation avec acte : 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS'2006), Tokyo (Japon), 5-9 Novembre 2006, pp.1217-1219 , N° 06416
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108341Liquid loading of silicon-based cantilevers using electrowetting actuation for microspotting applications
T.LEICHLE, D.SAYA, P.BELAUBRE, J.B.POURCIEL, F.MATHIEU, J.P.LAUR, L.NICU, C.BERGAUD
NANO, 2I, CIP, CNRS-IIS
Revue Scientifique : Sensors and Actuators A: Physical, Vol.132, N°2, pp.590-596, Novembre 2006 , N° 05027
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