7documents trouvés
Flow profile measurement in microchannel using the optical feedback interferometry sensing technique
L.CAMPAGNOLO, M.NIKOLIC, J.PERCHOUX, Y.L.LIM, K.BERTLING, K.LOUBIERE, L.PRAT, A.D.RAKIC, T.BOSCH
OSE, Queensland, LGC
Revue Scientifique : Microfluidics and Nanofluidics, Vol.14, N°1-2, pp.113-119, Janvier 2013 , N° 13003
Lien : http://hal.archives-ouvertes.fr/hal-00757538
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Abstract
The need to accurately measure flow profiles in microfluidic channels is well recognised. In this work, we present a new optical feedback interferometry (OFI) flow sensor that accurately measures local velocity in fluids and enables reconstruction of a velocity profile inside a microchannel. OFI is a self-aligned interferometric technique that uses the laser as both the transmitter and the receiver thus offering high sensitivity, fast response, and a simple and compact optical design. The system described here is based on a commercial semiconductor laser and has been designed to achieve a micrometer-range spatial resolution. The sensor performance was validated by reconstructing the velocity profile inside a circular cross-section flow-channel with 320 µm internal diameter, with a relative error smaller than 1.8 %. The local flow velocity is directly measured, thus avoiding the need for model based profile calculation and uncertainties inherent to this approach. The system was validated by successfully extracting the flow profiles in both Newtonian and shear-thinning liquids.
A new optical feedback interferometer for measuring red blood cell velocity distributions in individual capillaries: a feasibility study in microchannels
L.CAMPAGNOLO, S.ROMAN, J.PERCHOUX, S.LORTHOIS
OSE, TEAM, IMFT
Manifestation avec acte : Congrès Annuel de la Société de Bioméchanique 2012 du 16 octobre au 19 octobre 2012, Toulouse (France), Prix du meilleur poster, 2012, 2p. , N° 12347
Lien : http://hal.archives-ouvertes.fr/hal-00714045
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Abstract
The dynamics of blood flow in microvascular networks is of great importance in the exchange of nutrient and waste substances between blood and living tissues. In these vessels of diameter less than 100µm, the development of quantitative methods for measuring the velocity of red blood cells (RBCs) is still challenging. In this context, the Dual-Slit (DS) technique, a temporal correlation technique, is commonly used. Our group has recently shown that, provided that several operational conditions are fulfilled, this technique can provide a precise measurement of the transverse velocity profile of RBCs. The measured velocities are maximal velocities in the depth of the channel . However, this technique requires expensive equipment (high speed camera) and the related data-treatment is time consuming. Moreover, the duration of the acquisition is long (typically 2 to 40s). For these reasons, on line measurements, especially in cases of transient regimes, are not possible. The aim of the present work is to determine whether Optical Feedback Interferometry, a new optical technique in the microfluidic domain which is based on the optical feedback effect in laser diodes, can be used to perform quantitative measurements of RBCs velocity in channels of size less than 100µm. Optical Feedback Interferometers (OFI) are indeed compact, low cost and simple sensors. They are known for providing much shorter response times than DS, currently lower than 10ms, while keeping the precision of traditional Laser Doppler Interferometers. This technique has been previously applied and validated to measure velocity profiles in 300µm diameter channels, but its feasibility in smaller channels is still to be demonstrated. For that purpose, the velocity profiles obtained by OFI and DS are compared, using PDMS microchannels and spheric monodisperse particle suspensions in set-up configurations where the DS has been previously validated.
A new optical feedback interferometer for measuring red blood cell velocity distributions in individual capillaries: a feasibility study in microchannels
L.CAMPAGNOLO, S.ROMAN, J.PERCHOUX, S.LORTHOIS
OSE, TEAM, IMFT
Revue Scientifique : Computer Methods in Biomechanics and Biomedical Engineering, Supplément 1, Vol.15, pp.104-105, Septembre 2012 , N° 12347
Lien : http://hal.archives-ouvertes.fr/hal-00714045
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Plus d'informations
Abstract
The dynamics of blood flow in microvascular networks is of great importance in the exchange of nutrient and waste substances between blood and living tissues. In these vessels of diameter less than 100µm, the development of quantitative methods for measuring the velocity of red blood cells (RBCs) is still challenging. In this context, the Dual-Slit (DS) technique, a temporal correlation technique, is commonly used. Our group has recently shown that, provided that several operational conditions are fulfilled, this technique can provide a precise measurement of the transverse velocity profile of RBCs. The measured velocities are maximal velocities in the depth of the channel . However, this technique requires expensive equipment (high speed camera) and the related data-treatment is time consuming. Moreover, the duration of the acquisition is long (typically 2 to 40s). For these reasons, on line measurements, especially in cases of transient regimes, are not possible. The aim of the present work is to determine whether Optical Feedback Interferometry, a new optical technique in the microfluidic domain which is based on the optical feedback effect in laser diodes, can be used to perform quantitative measurements of RBCs velocity in channels of size less than 100µm. Optical Feedback Interferometers (OFI) are indeed compact, low cost and simple sensors. They are known for providing much shorter response times than DS, currently lower than 10ms, while keeping the precision of traditional Laser Doppler Interferometers. This technique has been previously applied and validated to measure velocity profiles in 300µm diameter channels, but its feasibility in smaller channels is still to be demonstrated. For that purpose, the velocity profiles obtained by OFI and DS are compared, using PDMS microchannels and spheric monodisperse particle suspensions in set-up configurations where the DS has been previously validated.
Vélocimétrie par réinjection optique appliquée à la mesure d'écoulements microfluidiques
L.CAMPAGNOLO
OSE
Manifestation sans acte : Journées Nationales du Réseau Doctoral en Microélectronique (JNRDM 2012), Marseille (France), 18-20 Juin 2012, 4p. , N° 12345
Lien : http://hal.archives-ouvertes.fr/hal-00714049
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Le phénomène de rétro-injection optique (interférences de deux ondes dans le milieu actif d'une diode laser) est utilisé pour des applications métrologiques telles que la mesure de vitesse ou de distance. Dans le cadre de ce projet, cette technologie est appliquée à la mesure de profil d'écoulement dans des puces microfluidiques. L'évolution du signal en fonction de la taille et de la forme du canal microfluidique, du volume de mesure, de la concentration et de la taille des particules est étudiée. Une nouvelle classe de capteurs non invasifs, faible coût et intégrable, est présentée pour la mesure de la microcirculation sanguine in-vivo.
Vélocimétrie par réinjection optique appliquée à la mesure d'écoulements microfluidiques
L.CAMPAGNOLO, M.NIKOLIC, J.PERCHOUX
OSE, Queensland
Manifestation avec acte : Colloque International Francophone du club CMOI/SFO "Contrôles et Mesures Optiques pour l'Industrie" , Lille (France), 21-25 Novembre 2011, 6p. , N° 11808
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126599Flow profile measurement in micro-channels using changes in laser junction voltage due to self-mixing effect
M.NIKOLIC, Y.L.LIM, S.WILSON, A.D.RAKIC, L.CAMPAGNOLO, J.PERCHOUX, T.BOSCH
Queensland, OSE
Manifestation avec acte : IEEE SENSORS 2011, Limerick (Irelande), 28-31 Octobre 2011, 4p. , N° 11812
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126607Measurement of flows in micro-channels through self-mixing effect in a laser diode
L.CAMPAGNOLO, J.CSONT, M.NIKOLIC, J.PERCHOUX, T.BOSCH
OSE, Queensland
Manifestation avec acte : International Conference on Microtechnologies in Medicine and Biololy (MMB 2011), Lucerne (Suisse), 4-6 Mai 2011, 2p. , N° 11815
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