Laboratoire d’Analyse et d’Architecture des Systèmes
L.CAMPAGNOLO, M.NIKOLIC, J.PERCHOUX, Y.L.LIM, K.BERTLING, K.LOUBIERE, L.PRAT, A.D.RAKIC, T.BOSCH
OSE, Queensland, LGC
Revue Scientifique : Microfluidics and Nanofluidics, Vol.14, N°1-2, pp.113-119, Janvier 2013 , N° 13003
Lien : http://hal.archives-ouvertes.fr/hal-00757538
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The need to accurately measure flow profiles in microfluidic channels is well recognised. In this work, we present a new optical feedback interferometry (OFI) flow sensor that accurately measures local velocity in fluids and enables reconstruction of a velocity profile inside a microchannel. OFI is a self-aligned interferometric technique that uses the laser as both the transmitter and the receiver thus offering high sensitivity, fast response, and a simple and compact optical design. The system described here is based on a commercial semiconductor laser and has been designed to achieve a micrometer-range spatial resolution. The sensor performance was validated by reconstructing the velocity profile inside a circular cross-section flow-channel with 320 µm internal diameter, with a relative error smaller than 1.8 %. The local flow velocity is directly measured, thus avoiding the need for model based profile calculation and uncertainties inherent to this approach. The system was validated by successfully extracting the flow profiles in both Newtonian and shear-thinning liquids.
L.CAMPAGNOLO, S.ROMAN, J.PERCHOUX, S.LORTHOIS
OSE, TEAM, IMFT
Manifestation avec acte : Congrès Annuel de la Société de Bioméchanique 2012 du 16 octobre au 19 octobre 2012, Toulouse (France), Prix du meilleur poster, 2012, 2p. , N° 12347
Lien : http://hal.archives-ouvertes.fr/hal-00714045
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The dynamics of blood flow in microvascular networks is of great importance in the exchange of nutrient and waste substances between blood and living tissues. In these vessels of diameter less than 100µm, the development of quantitative methods for measuring the velocity of red blood cells (RBCs) is still challenging. In this context, the Dual-Slit (DS) technique, a temporal correlation technique, is commonly used. Our group has recently shown that, provided that several operational conditions are fulfilled, this technique can provide a precise measurement of the transverse velocity profile of RBCs. The measured velocities are maximal velocities in the depth of the channel . However, this technique requires expensive equipment (high speed camera) and the related data-treatment is time consuming. Moreover, the duration of the acquisition is long (typically 2 to 40s). For these reasons, on line measurements, especially in cases of transient regimes, are not possible. The aim of the present work is to determine whether Optical Feedback Interferometry, a new optical technique in the microfluidic domain which is based on the optical feedback effect in laser diodes, can be used to perform quantitative measurements of RBCs velocity in channels of size less than 100µm. Optical Feedback Interferometers (OFI) are indeed compact, low cost and simple sensors. They are known for providing much shorter response times than DS, currently lower than 10ms, while keeping the precision of traditional Laser Doppler Interferometers. This technique has been previously applied and validated to measure velocity profiles in 300µm diameter channels, but its feasibility in smaller channels is still to be demonstrated. For that purpose, the velocity profiles obtained by OFI and DS are compared, using PDMS microchannels and spheric monodisperse particle suspensions in set-up configurations where the DS has been previously validated.
L.CAMPAGNOLO, S.ROMAN, J.PERCHOUX, S.LORTHOIS
OSE, TEAM, IMFT
Revue Scientifique : Computer Methods in Biomechanics and Biomedical Engineering, Supplément 1, Vol.15, pp.104-105, Septembre 2012 , N° 12347
Lien : http://hal.archives-ouvertes.fr/hal-00714045
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The dynamics of blood flow in microvascular networks is of great importance in the exchange of nutrient and waste substances between blood and living tissues. In these vessels of diameter less than 100µm, the development of quantitative methods for measuring the velocity of red blood cells (RBCs) is still challenging. In this context, the Dual-Slit (DS) technique, a temporal correlation technique, is commonly used. Our group has recently shown that, provided that several operational conditions are fulfilled, this technique can provide a precise measurement of the transverse velocity profile of RBCs. The measured velocities are maximal velocities in the depth of the channel . However, this technique requires expensive equipment (high speed camera) and the related data-treatment is time consuming. Moreover, the duration of the acquisition is long (typically 2 to 40s). For these reasons, on line measurements, especially in cases of transient regimes, are not possible. The aim of the present work is to determine whether Optical Feedback Interferometry, a new optical technique in the microfluidic domain which is based on the optical feedback effect in laser diodes, can be used to perform quantitative measurements of RBCs velocity in channels of size less than 100µm. Optical Feedback Interferometers (OFI) are indeed compact, low cost and simple sensors. They are known for providing much shorter response times than DS, currently lower than 10ms, while keeping the precision of traditional Laser Doppler Interferometers. This technique has been previously applied and validated to measure velocity profiles in 300µm diameter channels, but its feasibility in smaller channels is still to be demonstrated. For that purpose, the velocity profiles obtained by OFI and DS are compared, using PDMS microchannels and spheric monodisperse particle suspensions in set-up configurations where the DS has been previously validated.
R.TEYSSEYRE, F.BONY, J.PERCHOUX, T.BOSCH
OSE
Revue Scientifique : Optics Letters, Vol.37, N°18, pp.3771-3773, Septembre 2012 , N° 12738
Lien : http://hal.archives-ouvertes.fr/hal-00757566
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In this Letter, we experimentally show that transient phenomenons in self-mixing signals from a moving target contain information about the target reflectivity and distance. These transient phenomenons are well explained with a dynamical model of the laser diode, which is used to trace an abacus giving the target reflectivity and distance from a measured high-bandwidth, self-mixing signal.
L.CAMPAGNOLO, M.NIKOLIC, J.PERCHOUX
OSE, Queensland
Manifestation avec acte : Colloque International Francophone du club CMOI/SFO "Contrôles et Mesures Optiques pour l'Industrie" , Lille (France), 21-25 Novembre 2011, 6p. , N° 11808
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126599R.S.MATHARU, J.PERCHOUX, A.D.RAKIC
Queensland, OSE
Manifestation avec acte : IEEE SENSORS 2011, Limeryck (Irelande), 28-31 Octobre 2011, 4p. , N° 11810
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126603M.NIKOLIC, Y.L.LIM, S.WILSON, A.D.RAKIC, L.CAMPAGNOLO, J.PERCHOUX, T.BOSCH
Queensland, OSE
Manifestation avec acte : IEEE SENSORS 2011, Limerick (Irelande), 28-31 Octobre 2011, 4p. , N° 11812
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126607R.S.MATHARU, J.PERCHOUX, R.KLIESE, Y.L.LIM, A.D.RAKIC
Queensland, OSE
Revue Scientifique : Optics Letters, Vol.36, N°18, pp.3690-3692, Septembre 2011 , N° 11807
Lien : http://hal.archives-ouvertes.fr/hal-00757555
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We demonstrate a method for maintaining the maximum signal-to-noise ratio (SNR) of the signal obtained from the self-mixing sensor based on a vertical-cavity surface-emitting laser (VCSEL). It was found that the locus of the maximum SNR in the current-temperature space can be well approximated by a simple analytical model related to the temperature behavior of the VCSEL threshold current. The optimum sensor performance is achieved by tuning the laser current according to the proposed model, thus enabling the sensor to operate without temperature stabilization in a wide temperature range between −20 °C and +80 °C .
L.CAMPAGNOLO, J.CSONT, M.NIKOLIC, J.PERCHOUX, T.BOSCH
OSE, Queensland
Manifestation avec acte : International Conference on Microtechnologies in Medicine and Biololy (MMB 2011), Lucerne (Suisse), 4-6 Mai 2011, 2p. , N° 11815
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126613G.QUADRI, B.ONILLON, O.LLOPIS, J.PERCHOUX, J.C.MOLLIER
CNES, CISHT, SUPAERO
Rapport de Contrat : Contrat Région Midi Pyrénées, Mars 2005, 59p. , N° 05200
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