The ISI team contributions aim to make easier the design of complex systems by improving development life-cycle processes, particularly requirement management, modeling, model integration, verification and validation, simulation and virtual prototyping, in a process, method and tool vision. The uniqueness of the ISI group's work is linked to its members' will to adapt the processes and models to heterogenous systems. The study of heterogenous systems requires a better communication between the different communities, for instance as an information and model exchange gateway.